The Problem Malaria is one of the most severe public health problems worldwide, a widespread and deadly disease concentrated in equatorial regions--primarily in sub-Saharan Africa, where ninety percent of malaria-related deaths occur. Each year, over 200 million people become infected with malaria. Of those cases, the disease will prove fatal for 438,000 people. Seventy percent of these deaths are of children under five years old, making malaria one of the leading causes of child mortality in Africa. Even when non-fatal, malaria can damage children’s cognitive development. In many developing countries, malaria is the leading cause of death for pregnant women. Malaria is a drain on households and countries; it is estimated to cost Africa $12 billion every year in costs of health care, absenteeism, days lost in education, decreased productivity due to brain damage from cerebral malaria, and loss of investment and tourism.